Rhobust™ > Ligand Chemistry > High Specificity

High Specificity

Properties of mixed mode ligands

Mixed mode ligands are low molecular weight compounds that are designed to have a combination of binding interactions. Their structure usually consists of an aromatic core to which different hydrophilic or ionic substituents are attached. Ligand substituents influence the binding specificity; a combination of substitutents can be found through screening techniques, that can bind a single biomolecule even directly from feedstock. Mixed mode ligands are particularly useful when fragile compounds must be isolated in high yields because mild chemical conditions can be used to disrupt binding and recover the purified product.

Ligand Chemistry | High Specificity | Robustness